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What is Chemotherapy?

Chemotherapy is a cancer treatment that uses powerful drugs to target and destroy rapidly growing cancer cells. While it’s a cornerstone of cancer care, chemotherapy can also affect healthy cells, leading to side effects. It is often part of a broader treatment plan that may include surgery or radiation therapy.

How Does Chemotherapy Work?

Chemotherapy drugs interfere with the cell cycle, preventing cancer cells from dividing and spreading. These drugs are usually delivered through:

  • Intravenous (IV) Infusion: Directly into the bloodstream.
  • Oral Medications: Pills or capsules.
  • Injections: Administered into specific areas like muscles or the spine.

Types of Chemotherapy

  • Curative Chemotherapy

    • Aims to eliminate cancer entirely.
  • Adjuvant Chemotherapy

    • Given after surgery or radiation to kill remaining cancer cells.
  • Neoadjuvant Chemotherapy

    • Administered before surgery to shrink tumors for easier removal.
  • Palliative Chemotherapy

    • Focuses on relieving symptoms and improving quality of life in advanced cancer cases.

Cancers Treated with Chemotherapy

  • Chemotherapy is effective for various types of cancer, including:

    • Breast cancer
    • Lung cancer
    • Colorectal cancer
    • Lymphomas and leukemias

Benefits of Chemotherapy

  • Shrinks tumors to alleviate symptoms.
  • Reduces the risk of recurrence when combined with other treatments.
  • Destroys cancer cells in multiple areas of the body (systemic treatment).

Side Effects of Chemotherapy

While effective, Chemotherapy often affects healthy cells, leading to side effects such as:

  • Fatigue: One of the most common side effects.
  • Hair Loss: Temporary, as hair usually regrows after treatment.
  • Nausea and Vomiting: Manageable with medications.
  • Weakened Immune System: Increased risk of infections.
  • Neuropathy: Tingling or numbness in hands and feet.

Managing Chemotherapy Side Effects

  • Stay Hydrated:

    • Drink plenty of fluids to flush toxins from your system.
  • Eat a Balanced Diet:

    • Focus on small, nutritious meals to maintain strength.
  • Prevent Infections:

    • Wash hands frequently and avoid crowded places during low immunity periods.
  • Communicate with Your Healthcare Team:

    • Report side effects promptly for effective management.

What to Expect During Chemotherapy

  • Preparation:

    • Blood tests and a consultation with your oncologist to determine the right dosage.
  • Treatment Sessions:

    • Sessions last from 30 minutes to several hours, depending on the regimen.
  • Post-Treatment:

    • Rest and follow any specific care instructions provided by your doctor.

Recent Advances in Chemotherapy

  • Targeted Chemotherapy:

    • Focuses specifically on cancer cells, minimizing damage to healthy tissue.
  • Immuno-Chemotherapy:

    • Combines chemotherapy with immunotherapy for enhanced results.
  • Nanoparticle-Based Delivery:

    • Improves drug delivery precision, reducing side effects.

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